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Publications

Scientific publications: 

2018

Borry P, Bentzen HB, Budin-Ljøsne I, Cornel MC, Howard HC, Feeney O, Jackson L, Mascalzoni D, Mendes Á, Peterlin B, Riso B, Shabani M, Skirton H, Sterckx S, Vears D, Wjst M, Felzmann H. The challenges of the expanded availability of genomic information: an agenda-setting paper. J Community Genet. 2018;9:103-116. PDF

Cornel MC. Responsible Implementation of Expanded Screening Programs for Genetic Diseases at the Beginning of Life. OBM Genetics 2018;2:013. PDF

De Groot-van der Mooren MD, Tamminga S, Oepkes D, Weijerman ME, Cornel MC. Older mothers and increased impact of prenatal screening. Stable Down syndrome livebirth prevalence in the Netherlands for the period 2000-2013. Eur J Hum Genet. 2018;26:157-165. PDF

De Wert G, Heindryckx B, Pennings G, Clarke A, Eichenlaub-Ritter U, van El CG, Forzano F, Goddijn M, Howard HC, Radojkovic D, Rial-Sebbag E, Dondorp W, Tarlatzis BC, Cornel MC; European Society of Human Genetics and the European Society of Human Reproduction and Embryology. Responsible innovation in human germline gene editing: Background document to the recommendations of ESHG and ESHRE. Eur J Hum Genet. 2018;26:450-470. PDF

De Wert G, Pennings G, Clarke A, Eichenlaub-Ritter U, van El CG, Forzano F, Goddijn M, Heindryckx B, Howard HC, Radojkovic D, Rial-Sebbag E, Tarlatzis BC, Cornel MC; European Society of Human Genetics and the European Society of Human Reproduction and Embryology. Human germline gene editing: Recommendations of ESHG and ESHRE. Eur J Hum Genet. 2018;26:445-449. PDF

Harper JC, Aittomäki K, Borry P, Cornel MC, de Wert G, Dondorp W, Geraedts J, Gianaroli L, Ketterson K, Liebaers I, Lundin K, Mertes H, Morris M, Pennings G, Sermon K, Spits C, Soini S, van Montfoort APA, Veiga A, Vermeesch JR, Viville S, Macek M Jr; on behalf of the European Society of Human Reproduction and Embryology and European Society of Human Genetics. Recent developments in genetics and medically assisted reproduction: from research to clinical applications.Eur J Hum Genet. 2018;26:12-33. PDF

Holtkamp KCA, Lakeman P, Hader H, Jans SMJP, Hoenderdos M, Playfair HAM, Cornel MC, Peters M, Henneman L. Experiences of a high-risk population with prenatal hemoglobinopathy carrier screening in a primary care setting: A qualitative study. J Genet Couns 2018;27:635-46 PDF

Howard HC, van El CG, Forzano F, Radojkovic D, Rial-Sebbag E, de Wert G, Borry P, Cornel MC; Public and Professional Policy Committee of the European Society of Human Genetics. One small edit for humans, one giant edit for humankind? Points and questions to consider for a responsible way forward for gene editing in humans. Eur J Hum Genet. 2018;26:1-11 PDF

Jackson L, O'Connor A, Paneque M, Curtisova V, Lunt PW, Pourova RK, Macek M Jr, Stefansdottir V, Turchetti D, Campos M, Henneman L, Godino L, Skirton H, Cornel MC. The Gen-Equip Project - evaluation and impact of genetics e-learning resources for primary care in six European languages. Genet Med. 2018 Jul 27. doi: 10.1038/s41436-018-0132-3. PDF

Rahimzadeh V, Schickhardt C, Knoppers BM, Sénécal K, Vears DF, Fernandez CV, Pfister S, Plon S, Terry S, Williams J, Williams MS, Cornel M, Friedman JM. Key Implications of Data Sharing in Pediatric Genomics. JAMA Pediatr. 2018 Mar 19. doi: 10.1001/jamapediatrics.2017.5500. PDF

Samuel G, Howard HC, Cornel M, van El C, Hall A, Forzano F, Prainsack B. A response to the forensic genetics policy initiative's report "Establishing Best Practice for Forensic DNA Databases". Forensic Sci Int Genet. 2018;36: e19–e21. PDF

van Dijke I, Bosch L, Bredenoord AL, Cornel M, Repping S, Hendriks S. The ethics of clinical applications of germline genome modification: a systematic review of reasons. Hum Reprod. 2018 Aug 6. doi: 10.1093/humrep/dey257. PDF

Van El CG, Baccolini V, Piko P, Cornel MC. Stakeholder Views on Active Cascade Screening for Familial Hypercholesterolemia. Healthcare 2018, 6(3), 108; https://doi.org/10.3390/healthcare6030108 PDF

2017

Aymé S, Bockenhauer D, Day S, et al. (Conference Participants incl MC Cornel). Common Elements in Rare Kidney Diseases: Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney Int. 2017;92:796-808. PDF

Aymé S, Cornel MC. The development of the public and professional policy committee. Eur J Hum Genet. 2017;25(s2):S29-S32. PDF

Cornel M. A higher impact of less specific preconception carrier screening: a plea for a “one size fits all” approach? (Editorial) Journal of Xiangya Medicine  2017;2:14. PDF

Cornel MC. Blame - a novel by Tony Holtzman. J Comm Genetics 2017;8:253-254. PDF

Cornel MC, Bonham VL.Genomics for all in the 21st century? J Comm Genetics 2017;8:249-251. PDF

Cornel MC, van El CG. Barriers and Facilitating Factors for Implementation of Genetic Services: A Public Health Perspective. Frontiers in Public Health 2017;5:195. PDF

Friedman JM, Cornel MC, Goldenberg AJ, Lister KJ, Sénécal K, Vears DF; Global Alliance for Genomics and Health Regulatory and Ethics Working Group Paediatric Task Team. Genomic newborn screening: public health policy considerations and recommendations. BMC Med Genomics. 2017;10:9. PDF

Holtkamp KCA, Mathijssen IB, Lakeman P, Van Maarle M, Dondorp WJ, Henneman L, Cornel MC. Factors for successful implementation of population-based expanded carrier screening: Learning from existing initiatives. Eur J Publ Health 2017;17:146.PDF

Holtkamp KCA, Vos EM, Rigter T, Lakeman P, Henneman L, Cornel MC. Stakeholder perspectives on the implementation of genetic carrier screening in a changing landscape. BMC Health Services Research  2017; 17:146 PDF

Hörster F, Kölker S, Loeber JG, Cornel MC, Hoffmann GF, Burgard P. Newborn Screening Programmes in Europe, Arguments and Efforts Regarding Harmonisation: Focus on Organic Acidurias. JIMD Rep. 2017;32:105-115 PDF

Jansen ME, Lister KJ, van Kranen H, Cornel MC. Policy Making in Newborn Screening Needs a Structured and Transparent Approach. Frontiers in Public Health 2017;5:53 https://doi.org/10.3389/fpubh.2017.00053

Jansen ME, Rigter T, Rodenburg W, Fleur TMC, Houwink EJF, Weda M, Cornel MC. Review of the Reported Measures of Clinical Validity and Clinical Utility as Arguments forthe Implementation of Pharmacogenetic Testing: A Case Study of Statin-Induced Muscle Toxicity. Front. Pharmacol. 2017;8:555.PDF

Lipka AF, Vrinten C, van Zwet EW, Schimmel KJM, Cornel MC, Weinreich SS, Verschuuren J, Kuijpers MR. Ephedrine treatment for autoimmune myasthenia gravis. Neuromuscul Disord. 2017;27:259-265. PDF

Paneque M, Cornel MC, Curtisova V, Houwink E, Leigh Jackson L, Kent A, Lunt P, Macek M, Stefansdottir V, Turchetti D, Skirton H. Implementing genetic education in primary care: the Gen-Equip programme. Journal of Community Genetics 2017;8:147-150. PDF

Tamminga S, van Dussen L, Verweij EJ, de Boer MA, Cornel MC, Henneman L. What do people want to know about NIPT? Content analysis of questions emailed to national NIPT information websites. Prenat Diagn. 2017; 37: 412-415 PDF

van Schendel RV, Kater-Kuipers A, van Vliet-Lachotzki EH, Dondorp WJ, Cornel MC, Henneman L. What Do Parents of Children with Down Syndrome Think about Non-Invasive Prenatal Testing (NIPT)? J Genet Couns. 2017;26:522-531 PDF

van Schendel RV, van El CG, Pajkrt E, Henneman L, Cornel MC. Implementing non-invasive prenatal testing for aneuploidy in a national healthcare system: global challenges and national solutions.  BMC Health Serv Res. 2017;17:670 PDF

Weinreich SS, Vrinten C, Kuijpers MR, Lipka AF, Schimmel KJM, van Zwet EW, Gispen-de Wied C, Hekster YA, Verschuuren JJGM, Cornel MC. Aggregated N-of-1 trials for unlicensed medicines for small populations: an assessment of a trial with ephedrine for myasthenia gravis. Orphanet J Rare Dis. 2017;12:88. PDF

2016

Henneman L, Borry P, Chokoshvili D, Cornel MC, van El CG, Forzano F, Hall A, Howard H, Janssens S, Kayserili H, Lakeman P, Lucassen A, Metcalfe SA, Vidmar L, de Wert G, Dondorp WJ, Peterlin B on behalf of the European Society of Human Genetics (ESHG). Responsible implementation of expanded carrier screening. Eur J Hum Genet 2016;24:e1-e12. PDF

Knoppers BM, Sénécal K, Boisjoli J, Borry P, Cornel MC, Fernandez CV, Grewal J, Holm IA, Nelson E, Pinxten W, Shabani M, Tassé AM, Zawati M, Wright Clayton E, on behalf of the P3G International Paediatric Research Platform. Recontacting Pediatric Research Participants for Consent When They Reach the Age of Majority. IRB: Ethics & Human research 2016;38(6):1-9. PDF

Tamminga S, van Maarle M, Henneman L, Oudejans CBM, Cornel MC, Sistermans EA. Maternal Plasma DNA and RNA Sequencing for Prenatal Testing. Advances in Clinical Chemistry 2016;74:63-102. PDF

van Teeffelen SR, Douglas DMW, Van El CG, Weinreich SS, Henneman L, Radstake M, Cornel MC. Mothers' views on longer storage of neonatal dried blood spots for specific secondary uses. Public Health Genomics 2016;19:25-33. PDF

Wijdenes M, Henneman L, Dondorp WJ, Cornel MC, Timmermans DR. Users evaluate a detailed familial risk questionnaire as valuable and no more time consuming than a simple enquiry in a web-based diabetes risk assessment tool. Public Health 2016;130:87-90. PDF

2015

Bosma AR, Rigter T, Weinreich SS, Cornel MC, Henneman L. A genetic diagnosis of maturity-onset diabetes of the young (MODY): Experiences of patients and family members. Diabet Med. 2015;32:1385-92. PDF

Cornel MC. Neonatale screening: nieuwe aanbevelingen van de Gezondheidsraad. Ned Tijdschr Geneeskd. 2015;159:A9115. PDF

De Smit D, Weinreich SS, Cornel MC. Effects of a simple educational intervention in well-baby clinics on women's knowledge about and intake of folic acid supplements in the periconceptional period: a controlled trial. Public Health Nutrition 2015;18:1119-26. PDF

Dondorp W, De Wert G, Bombard Y, Bianchi DW, Bergmann C, Borry P, Chitty LS, Fellmann F, Forzano F, Hall A, Henneman L, Howard HC, Lucassen A, Ormond K, Peterlin B, Radojkovic D, Rogowski W, Soller M, Tibben A, Tranebjærg L, Van El CG, Cornel MC, on behalf of the European Society of Human Genetics (ESHG) and the American Society of Human Genetics (ASHG). Non-invasive prenatal testing for aneuploidy and beyond: challenges of responsible innovation in prenatal screening. Eur J Hum Genet 2015;23:1438-50. PDF

Dondorp W, de Wert G, Bombard Y, Bianchi DW, Bergmann C, Borry P, Chitty LS, Fellmann F, Forzano F, Hall A, Henneman L, Howard HC, Lucassen A, Ormond K, Peterlin B, Radojkovic D, Rogowski W, Soller M, Tibben A, Tranebjærg L, van El CG, Cornel MC. Non-invasive prenatal testing for aneuploidy and beyond: challenges of responsible innovation in prenatal screening. Summary and recommendations. Eur J Hum Genet. advanced online publication, 1 April 2015; doi:10.1038/ejhg.2015.56 PDF

Hehir-Kwa JY, Claustres M, Hastings RJ, van Ravenswaaij-Arts C, Christenhusz G, Genuardi M, Melegh B, Cambon-Thomsen A, Patsalis P, Vermeesch J, Cornel MC, Searle B, Palotie A, Capoluongo E, Peterlin B, Estivill X, Robinson PN. Towards a European consensus for reporting incidental findings during clinical NGS testing. Eur J Hum Genet. 2015;23:1601-6. PDF

Henneman L, Mc Bride CM, Cornel MC, Duquette D, Qureshi N. Screening for familial hypercholesterolemia in children: what can we learn from adult screening programs? Healthcare 2015;3:1018-1030. PDF

Houwink EJ, Muijtjens AM, van Teeffelen SR, Henneman L, Rethans JJ, Jacobi F, van der Jagt L, Stirbu I, van Luijk SJ, Stumpel CT, Meijers-Heijboer HE, van der Vleuten C, Cornel MC, Dinant GJ. Effect of Comprehensive Oncogenetics Training Interventions for General Practitioners, Evaluated at Multiple Performance Levels. PLoS One. 2015;10(4):e0122648. PDF

Howard HC, Knoppers BM, Cornel MC, Wright Clayton E, Sénécal K, Borry P; endorsed by the European Society of Human Genetics; the P3G International Paediatric Platform; the Human Genome Organisation; and the PHG Foundation. Whole-genome sequencing in newborn screening? A statement on the continued importance of targeted approaches in newborn screening programmes. Eur J Hum Genet 2015;23:1593–1600 PDF

Kelmemi W, Teeuw ME, Bochdanovits Z, Ouburg S, Jonker MA, Alkuraya F, Hashem M, Kayserili H, van Haeringen A, Sheridan E, Masri A, Cobben JM, Rizzu P, Kostense PJ, Dommering CJ, Henneman L, Bouhamed-Chaabouni H, Heutink P, Ten Kate LP, Cornel MC. Determining the genome-wide kinship coefficient seems unhelpful in distinguishing consanguineous couples with a high versus low risk for adverse reproductive outcome. BMC Med Genet. 2015 Jul 20;16:50. doi: 10.1186/s12881-015-0191-0. PDF

Severin F, Borry P, Cornel MC, Daniels N, Fellmann F, Hodgson SV, Howard HC, John J, Kayserili H, Kent A, Koerber F, Kristoffersson U, Kroese M, Lewis C, Marckmann G, Meyer P, Pfeufer A, Schmidtke J, Skirton H, Rogowski WH for the EuroGentest and ESHG / PPPC Priority Consortium. Points to consider for prioritizing clinical genetic testing services: a European consensus process oriented at accountability for reasonableness. Eur J Hum Genet. 2015;23:729-35.PDF

Tamminga S, van Schendel RV, Rommers W, Bilardo CM, Pajkrt E, Dondorp WJ, van Maarle M, Cornel MC, Henneman L. Changing to NIPT as a first-tier screening test and future perspectives: Opinions of health professionals. Prenatal Diagnosis 2015;35:1316-23. PDF

Temel S, van Voorst SF, de Jong-Potjer LC, Waelput AJ, Cornel MC, de Weerd SR, Denktaş S, Steegers EA. The Dutch national summit on preconception care: a summary of definitions, evidence and recommendations. J Community Genet. 2015;6:107-15. PDF

van der Zwaag AM, Weinreich SS, Bosma AR, Rigter T, Losekoot M, Henneman L, Cornel MC. Current and best practices of genetic testing for Maturity Onset Diabetes of the Young (MODY): Views of professional experts. Public Health Genomics 2015;18:52–59 PDF

Vrinten C, Lipka AF, van Zwet EW, Schimmel KJM, Cornel MC, Kuijpers MR, Hekster YA, Weinreich SS, Verschuuren JJGM. Ephedrine as add-on therapy for patients with myasthenia gravis: protocol for a series of randomised, placebo-controlled n-of-1 trials. BMJ Open 2015;5:e007863 doi:10.1136/bmjopen-2015-007863 PDF

Weinreich SS, Bosma A, Henneman L, Rigter T, Spruit CMJ, Grimbergen JEMA, Breuning MH, de Koning EJP,  Losekoot M, Cornel MC. A decade of molecular genetic testing for MODY: a retrospective study of utilization in The Netherlands. Eur J Hum Genet 2015;23:29–33 PDF

2014

Boccia S, Mc Kee M, Adany R, Boffetta P, Burton H, Cambon-Thomsen A, Cornel MC, Gray M, Jani A, Maria Knoppers B, Khoury MJ, Meslin EM, Van Duijn CM, Villari P, Zimmern R, Cesario A, Puggina A, Colotto M, Ricciardi W. Beyond public health genomics: proposals from an international working group. Eur J Public Health 2014;24:876-8. PDF

Bortolus R, Blom F, Filippini F, van Poppel MNM, Leoncini E, de Smit DJ, Benetollo PP, Cornel MC, de Walle HEK, Mastroiacovo P. Prevention of congenital malformations and other adverse pregnancy outcomes with 4.0 mg of folic acid: community-based randomized clinical trial in Italy and the Netherlands. BMC Pregnancy and Childbirth 2014;14:166.  PDF

Cornel MC, Rigter T, Weinreich SS, Burgard P, Hoffmann GF, Lindner M, Loeber JG, Rupp K, Taruscio D, Vittozzi L. A framework to start the debate on neonatal screening policies in the EU - An Expert Opinion Document. Eur J Hum Genet. 2014;22:12-7. PDF

Cornel MC, van El CG, Borry P. The challenge of implementing genetic tests with clinical utility while avoiding unsound applications. Journal of Community Genetics 2014;5:7-12. PDF

de Groot- van der Mooren MD, Gemke RJBJ, Cornel MC, Weijerman ME. Diagnosing Down syndrome in newborns in the Netherlands: suspicion and communication with parents. Journal of Intellectual Disability Research 2014;58:953-61. PDF

Dondorp WJ, van El CG, de Wert GMWR, Cornel MC. Raw Data: Research and Health Care Goals Differ. Science 2014;343; 968-9. PDF

Harper J, Geraedts J, Borry P, Cornel MC, Dondorp WJ, Gianaroli L, Harton G, Milachich T, Kääriäinen H, Liebaers I, Morris M, Sequeiros J, Sermon K, Shenfield F, Skirton H, Soini S, Spits C, Veiga A, Vermeesch JR, Viville S, de Wert G, Macek M Jr; on behalf of ESHG, ESHRE and EuroGentest2. Current issues in medically assisted reproduction and genetics in Europe: research, clinical practice, ethics, legal issues and policy. Human Reproduction 2014;29(8):1603-9. PDF

Houwink EJF, Muijtjens AMM, Van Teeffelen SR, Henneman L, Rethans JJ, Van der Jagt L, Van Luijk SJ, Dinant GJ, Van der Vleuten C, Cornel MC. Effectiveness of oncogenetics training on general practitioners’ consultation skills: a randomized controlled trial. Genet Med. 2014;16:45-52. PDF

Houwink EJF, Van Teeffelen SR, Muijtjens AMM, Henneman L, Jacobi F, Van Luijk SJ, Dinant GJ,  Van der Vleuten C, Cornel MC. Sustained effects of online genetics education: A randomised controlled trial on oncogenetics. Eur J Hum Genet 2014; 22: 310–316. PDF

Kers JG, van Burg E, Stoop T, Cornel MC. Trends in genetic patent applications: the commercialization of academic intellectual property. Eur J Hum Genet 2014;22:1155-1159. PDF

Manniën J, de Jonge A, Cornel MC, Spelten E, Hutton EK. Factors associated with not using folic acid supplements preconceptionally. Public Health Nutr. 2014;17:2344–2350 PDF

Rigter T, Henneman H, Broerse JEW, Shepherd M, Blanco I, Kristoffersson U, Cornel MC. Developing a framework for implementation of genetic services: learning from examples of testing for monogenic forms of common diseases. J Community Genetics 2014;5:337-347 PDF

Rigter T, van Aart CJA, Elting MW, Waisfisz Q, Cornel MC, Henneman L. Informed consent for exome sequencing in diagnostics: exploring first experiences and views of professionals and patients. Clin Genet 2014: 85: 417–422. PDF

Teeuw ME, Loukili G, Ten Kate LP, Cornel MC, Henneman L. Consanguineous marriage and reproductive risk: Attitudes and understanding of ethnic groups practising consanguinity in Western society.Eur J Hum Genet 2014;22:452-457. PDF

Teeuw M, Waisfisz Q, Zwijnenburg PJ, Sistermans EA, Weiss MM, Henneman L, Ten Kate LP, Cornel MC, Meijers-Heijboer H. First steps in exploring prospective exome sequencing of consanguineous couples. Eur J Med Genet 2014;57:613-6. PDF

Ten Kate LP, Teeuw ME, Henneman L, Cornel MC. Consanguinity and Endogamy in the Netherlands: Demographic and Medical Genetic Aspects. Human Heredity 2014;77:161-166. PDF

Ten Kate LP, Teeuw M, Henneman L, Cornel MC. Comment on Gialluisi et al. Eur J Hum Genet 2014;22:157. PDF

van El CG, Rigter T, Reuser AJ, van der Ploeg AT, Weinreich SS, Cornel MC. Newborn screening for Pompe disease? A qualitative study exploring professional views. BMC Pediatr. 2014;14:203. PDF

Van Esch SCM, Nijkamp MD, Cornel MC, Snoek FJ. Illness representations of type 2 diabetes patients are associated with perceptions of diabetes threat in relatives. Journal of Health Psychology 2014;19:358-68. PDF

Vermeulen E, Henneman L, Van El CG, Cornel MC. Public attitudes towards preventive genomics and personal interest in genetic testing to prevent disease: a survey study. Eur J Pub Health 2014;24:768-75 PDF

2013

Cornel MC. Crossing the boundary between research and health care: P3G policy statement on return of results from population studies. (News & Commentaries) Eur J Hum Genet  2013; 21: 243–244. PDF

Fears R, ter Meulen V; EASAC–FEAM Working Group (Boccia S, Cornel MC, Delpech M, De Paepe A, Estivill X, Hansson M, Karalis K, Metspalu A, Propping P, Sequeiros J, Zimmern R, ter Meulen V, Fears R, Nöthen M). The perspective from EASAC and FEAM on direct-to-consumer genetic testing for health-related purposes. Eur J Hum Genet. 2013;21:703-7. PDF

Harper J, Geraedts J, Borry P, Cornel MC, Dondorp WJ, Gianaroli L, Harton G, Hristova-Milachich T, Kääriäinen H, Liebaers I, Morris M, Sequeiros J, Sermon K, Shenfield F, Skirton H, Soini S, Spits C, Veiga A, Vermeesch JR, Viville S, de Wert G, Macek M Jr. on behalf of ESHG, ESHRE and EuroGentest. Current issues in medically assisted reproduction and genetics in Europe: research, clinical practice, ethics, legal issues and policy. Eur J Hum Genet 2013;21:S1-S21 PDF

Henneman L, Van El CG, Cornel MC. Genetic testing and implications for personalized medicine: changes in public and healthcare professional perspectives (Editorial). Personalized Medicine 2013; 10: 217–219. PDF

Henneman L, Vermeulen E, van El CG, Claassen L, Timmermans DRM, Cornel MC. Public attitudes and beliefs about genetic testing revisited: Comparing opinions between 2002 and 2010. Eur J Hum Genet.  2013;21:793-9. PDF

Hens K, Van El CE, Borry P, Cambon-Thomsen A, Cornel MC, Forzano F, Lucassen A, Patch C, Tranebjaerg L, Vermeulen E, Salvaterra E, Tibben A, Dierickx K. Developing a policy for paediatric biobanks: principles for good practice. Eur J Hum Genet. 2013;21:2-7. PDF

Houwink EJ, Sollie AW, Numans ME, Cornel MC. Proposed roadmap to stepwise integration of genetics in family medicine and clinical research. Clin Transl Med. 2013 Feb 16;2(1):5. PDF

Jans SMPJ, Henneman L, de Jonge A, van El CG, van Tuyl L, Cornel MC, Lagro-Janssen ALM. “A morass of considerations”: Exploring attitudes towards primary care ethnicity-based haemoglobinopathy screening. Fam Pract. 2013;30:604-10. PDF

Rigter T, Henneman L, Kristoffersson U, Hall A, Yntema HG, Borry PM, Tönnies H, Waisfisz Q, Elting MW, Dondorp WJ, Cornel MC. Reflecting on earlier experiences with unsolicited findings: Points to consider for next generation sequencing and informed consent in diagnostics. Human Mutation 2013;34:1322-8. PDF

Van El CG, Cornel MC, Borry P, Hastings R, Fellmann F, Hodgson S, Howard HC, Cambon-Thomsen A, Knoppers B, Meijers-Heijboer H, Scheffer H, Tranebjaerg L, Dondorp W, de Wert GMWR, for the Public and Professional Policy Committee. Whole genome sequencing in health care. Recommendations of the European Society of Human Genetics. Eur J Hum Genet. 2013;21:580–4. PDF

Van El CG, Dondorp WJ, de Wert GM, Cornel MC. Call for prudence in whole-genome testing. Science. 2013;341:958-9. PDF

Van Esch SCM, Heideman WH, Cleijne W, Cornel MC, Snoek FJ. Health care providers’ perspective on using family history in the prevention of type 2 diabetes: a qualitative study including different disciplines. BMC Family Practice 2013;14:31. PDF

Wijdenes M, Henneman L, Qureshi N, Kostense PJ, Cornel MC, Timmermans DR. Using web-based familial risk information for diabetes prevention: a randomized controlled trial. BMC Public Health. 2013;13:485. PDF

 

2012

Burgard P, Rupp K, Lindner M, Haege G, Rigter T, Weinreich SS, Loeber JG, Taruscio D, Vittozzi L, Cornel MC, Hoffmann GF. Newborn screening programmes in Europe; arguments and efforts regarding harmonization. Part 2 - From screening laboratory results to treatment, follow-up and quality assurance. J Inherit Metab Dis. 2012;35:613-25. PDF

Cornel MC. The hopes and the hypes. Public Service Review: European Science & Technology 2012;16: 194-5. TEXT

Cornel MC, Gille JJP, Loeber JG, Vernooij-van Langen AMM, Dankert-Roelse J, Bolhuis PA. Improving test properties for neonatal cystic fibrosis screening in the Netherlands before the nationwide start by May 1st 2011. J Inherit Metab Dis. 2012;35:635-40. PDF

Cornel MC, van El CG, Dondorp WJ. The promises of genomic screening: building a governance infrastructure. Special issue: genetics and democracy. J Community Genetics 2012;3(2):73-7.  PDF

Douglas CM, van El CG, Faulkner A, Cornel MC. Governing biological material at the intersection of care and research: the use of dried blood spots for biobanking. Croat Med J. 2012;53:390-7. PDF

Douglas C, van El C, Radstake M, van Teeffelen S, Cornel MC. The politics of representation in the governance of emergent ‘secondary use’ biobanks: The case of dried blood spot cards in The Netherlands. Studies in Ethics, Law, and Technology 2012. Vol. 6: Iss. 1, Article 4. DOI: 10.1515/1941-6008.1178 PDF

Hastings R, de Wert G, Fowler B, Krawczak M, Vermeulen E, Bakker E, Borry P, Dondorp W, Nijsingh N, Barton D, Schmidtke J, van El CG, Vermeesch J, Stol Y, Carmen Howard H, Cornel MC. The changing landscape of genetic testing and its impact on clinical and laboratory services and research in Europe. Eur J Hum Genet. 2012;20:911-6. PDF

Houwink EJF, Henneman L, Westerneng M, Van Luijk SJ, Cornel MC, Dinant GJ, Van der Vleuten CV. Prioritisation of future genetics education for general practitioners: a Delphi study. Genet Med. 2012;14:323-9. PDF

Jans SMPJ, de Jonge A, Henneman L, Cornel MC, Lagro-Janssen AM. Attitudes of general practitioners and midwives towards ethnicity-based haemoglobinopathy carrier screening. Eur J Hum Gen 2012;20:1112-7. PDF

Jans SMPJ, van El CG, Houwaart ES, Westerman MJ, Janssens MJPA, Lagro-Janssen ALM, Plass AMC, Cornel MC. A case study of haemoglobinopathy screening in the Netherlands: witnessing the past, lessons for the future. Ethnicity & Health 2012;17:217-39.PDF

Loeber JG, Burgard P, Cornel MC, Rigter T, Weinreich SS, Rupp K, Hoffmann GF, Vittozzi L. Newborn screening programmes in Europe; arguments and efforts regarding harmonization. Part 1 - From blood spot to screening result. J Inherit Metab Dis. 2012;35:603-11. PDF

Rigter T, Weinreich SS, van El CG, de Vries JM, van Gelder CM, Güngör D, Reuser AJJ, Hagemans MLC, Cornel MC, van der Ploeg AT.Severely impaired health status at diagnosis of Pompe disease: A crosssectional analysis to explore the potential utility of neonatal screening, Molecular Genetics and Metabolism 2012;107:448-55, doi: 10.1016/j.ymgme.2012.09.017 PDF

Teeuw ME, Hagelaar A, Ten Kate LP, Cornel MC, Henneman L. Challenges in the Care for Consanguineous Couples: an Explorative Interview Study among General Practitioners and Midwives. BMC Family Practice 2012; 13:105. PDF

Van El CG, Pieters T, Cornel MC. Genetic screening and democracy: Lessons from debating genetic screening criteria in the Netherlands. Special issue: Genetics and Democracy. Community Genetics 2012;3(2):79-89  PDF

Van Esch SCM, Cornel MC, Geelhoed-Duijvestijn PHLM, Snoek FJ. Family communication as strategy in diabetes prevention: An observational study in families with Dutch and Surinamese South-Asian ancestry. Patiënt Education and Counseling 2012;87:23–29. PDF

 

Van Esch SCM, Nijkamp MD, Cornel MC, Snoek FJ. Patients’ intention to inform relatives about type 2 diabetes risk: the role of worry in the process of family risk disclosure. Diabetic Medicine 2012;29:e461-7. PDF

 

Weinreich SS, Rigter T, van El CG, Dondorp WJ, Kostense PJ, van der Ploeg AT, Reuser AJJ, Cornel MC, Hagemans MLC. Public support for neonatal screening for Pompe disease, a broad-phenotype condition. Orphanet Journal of Rare Diseases 2012;7:15. PDF

2011

Becker F, van El CG, Ibarreta D, Zika E, Hogarth S, Borry P, Cambon-Thomsen A, Cassiman JJ, Evers-Kiebooms G, Hodgson S, Janssens ACJW, Kaariainen H, Krawczak M, Kristoffersson U, Lubinski J, Patch C, Penchaszadeh VB, Read A, Rogowski W, Sequeiros J, Tranebjaerg L, van Langen IM, Wallace H, Zimmern R, Schmidtke J, Cornel MC. Genetic testing and common disorders in a public health framework: how to assess relevance and possibilities. Eur J Hum Genet 2011;19:S6-S44. PDF

Borry P, Henneman L, Lakeman P, Ten Kate LP, Cornel MC, Howard H. Preconceptional genetic carrier testing and the commercial offer directly-to-consumers. Human Reproduction 2011; 26:972-7 PDF

Henneman L, Timmermans DRM, Bouwman CM, Cornel MC, Meijers-Heijboer H. “A low risk is still a risk”: Exploring women’s attitudes toward genetic testing for breast cancer susceptibility in order to target disease prevention. Public Health Genomics 2011;14:238-247. PDF

Houwink EJF, van Luijk SJ, Henneman L, van der Vleuten C, Dinant GJ, Cornel MC. Genetic educational needs and role of genetics in primary care: a focus group study with multiple perspectives. BMC Family Practice 2011;12:5. PDF

Sikkens J, van Eijsden M, Bonsel G, Cornel MC. Validation of self-reported folic acid use in a multi-ethnic population: results of the Amsterdam Born Children and their Development study. Public Health Nutrition 2011;14:2022-8. PDF

Van El CG, Cornel MC on behalf of the ESHG Public and Professional Policy Committee. Genetic testing and common disorders in a public health framework. Recommendations of the European Society of Human Genetics. Eur J Hum Genet 2011;19:377-81. PDF

Vermeulen E, Schmidt MK, Cornel MC, Knoppers BM, van Leeuwen FE, Aaronson NK. Connective tissue: Cancer patients’ attitudes towards medical research using excised (tumour) tissue. Biosocieties 2011;6:466-486. PDF

Vermeulen E, van der Valk P, Koevoets JJ, Cornel MC, Schmidt MK. The BIO-PIN paradigm: 'access to' or 'return of' results? Nat Rev Cancer. 2011;11:895. PDF

Wijdenes-Pijl M, Dondorp WJ, Timmermans DRM, Cornel MC, Henneman L. Lay perceptions of predictive testing for diabetes based on DNA test results versus family history assessment: a focus group study. BMC Public Health 2011;11:535. PDF

2010

Borry P, Cornel MC, Howard HC. Where are you going, where have you been: a recent history of the direct-to-consumer genetic testing market. J Comm Genet 2010; 1: 101-106. PDF

Cornel MC. GenEthics and Religion. Book review. J Comm Genet 2010;1:159-160. PDF

Cornel MC, de Smit D. The Dutch folate supplementation education programme: challenges in raising awareness. Gynaecology Forum 2010;15(4):21-25. PDF

Forzano F, Borry P, Cambon-Thomsen A, Hodgson SV, Tibben A, de Vries P, van El C, Cornel M. Italian appeal court: A genetic predisposition to commit murder? Eur J Hum Genet 2010;18:519-21. PDF

Grosse SD, Rogowski WH, Ross LF, Cornel MC, Dondorp WJ, Khoury MJ. Population Screening for Genetic Disorders in the 21st Century: Evidence, Economics, and Ethics. Public Health Genomics 2010;13:106–115. PDF

Mihaescu R, Detmar SB, Cornel MC, van der Flier WM, Heutink P, Hol EM, Rikkert MG, van Duijn CM, Janssens AC. Translational Research in Genomics of Alzheimer's Disease: A Review of Current Practice and Future Perspectives. J Alzheimers Dis. 2010;20(4):967-80. PDF

Plass AMC, van El CG, Pieters T, Cornel MC. Neonatal screening for treatable and untreatable disorders: Prospective parents’ opinions. Pediatrics 2010;125:e99-106. PDF

Skirton H, Lewis C, Kent A, Coviello DA; Members of Eurogentest Unit 6 and ESHG Education Committee: Bloch-Zupan A, Darpoux FC, Cornel M, DeLozier C, Farndon P, Goetz P, Hodgson S, Houge G, Hulten M, Kosztolanyi G, Kucinskas V, Ozcelik T, Sequeiros J, Soller M, Tranebjaerg L. Genetic education and the challenge of genomic medicine: development of core competences to support preparation of health professionals in Europe. Eur J Hum Genet. 2010 Sep;18(9):972-7.PDF

Teeuw ME, Henneman L, Bochdanovits Z, Heutink P, Kuik DJ, Cornel MC, Ten Kate LP. Do consanguineous parents of a child affected by an autosomal recessive disease have more DNA identical-by-descent than similarly-related parents with healthy offspring? Design of a case-control study. BMC Medical Genetics 2010;11:113. PDF

Ten Kate LP, Al-Gazali L, Anand S, Bittles A, Cassiman JJ, Christianson A, Cornel MC, Hamamy J, Kääriäinen H, Kristoffersson U, Marais D, Penchaszadeh VB, Rahman P, Schmidtke J. Community Genetics. Its definition 2010. J Community Genetics 2010;1:19-22. PDF

Ten Kate LP, Teeuw M, Henneman L, Cornel MC. Autosomal recessive disease in children of consanguineous parents: Inferences from the proportion of compound heterozygotes. J Comm Genet 2010;1:37-40. PDF

van Esch SC, Cornel MC, Snoek FJ. "I am pregnant and my husband has diabetes. Is there a risk for my child?" A qualitative study of questions asked by email about the role of genetic susceptibility to diabetes. BMC Public Health. 2010;10:688. PDF

Vijverberg SJ, Pieters T, Cornel MC. Ethical and Social Issues in Pharmacogenomics Testing. Curr Pharm Des. 2010;16:245-52. Abstract

Bombard Y, Miller FA, Hayeems RZ, Avard D, Knoppers BM, Cornel MC, Borry P. Expanded newborn screening : is reproductive benefit an appropriate pursuit ? Nat Rev Genet. 2009;10:666-7.

Borry P, Evers-Kiebooms G, Cornel MC, Clarke A, Dierickx K, Public and Professional Policy Committee (PPPC) of the European Society of Human Genetics (ESHG). Genetic testing in asymptomatic minors. Eur J Hum Genet. 2009;17(6):711-9. 

European Society of Human Genetics. Genetic testing in asymptomatic minors: Recommendations of the European Society of Human Genetics. (Cornel M as collaborator) Eur J Hum Genet. 2009 Jun;17(6):720-1.

Lakeman P, Plass AM, Henneman L, Bezemer PD, Cornel MC, Ten Kate LP. Preconceptional ancestry-based carrier couple screening for cystic fibrosis and haemoglobinopathies: what determines the intention to participate or not and actual participation? Eur J Hum Genet. 2009;17:999-1009.

Patch C, Sequeiros J, Cornel MC. Genetic horoscopes: is it all in the genes? Points for regulatory control of direct-to-consumer genetic testing. Eur J Hum Genet. 2009;17:857-9.

Patch C, Sequeiros J, Cornel MC. Direct to consumer genetic tests (Letter). Eur J Hum Genet. 2009; 17:1111.

Plass AMC, Baars MJH, Cornel MC, Julian-Reynier C, Nippert I, Harris H, Kristoffersson U, Schmidtke J, Anionwu EN, Benjamin C, Challen K, Harris R, ten Kate LP. Testing the Children: Do Non-Genetic Health-Care Providers Differ in Their Decision to Advise Genetic Presymptomatic Testing on Minors? A Cross-Sectional Study in Five Countries in the European Union. Genetic Testing and Molecular Biomarkers 2009;13(3):367-376. 

Weinreich SS, de Lange-de Klerk ESM, Rijmen F, Cornel MC, de Kinderen M, Plass AMC. Raising awareness of carrier testing for hereditary haemoglobinopathies in high-risk ethnic groups in the Netherlands: a pilot study among the general public and primary care providers. BMC Public Health 2009, 9:338.

Aymé S, Matthijs G, Soini S; ESHG working party on Patenting and Licensing (incl. Cornel MC as collaborator). Patenting and licensing in genetic testing: recommendations of the European society of human genetics. Eur J Hum Genet. 2008;16 Suppl 1:S10-9.

Aymé S, Matthijs G, Soini S; ESHG working party on Patenting and Licensing (incl. Cornel MC as collaborator). Patenting and licensing in genetic testing. Eur J Hum Genet. 2008;16(4):405-11.

Lakeman P, Gille JJP, Dankert-Roelse JE, Heijerman HGM, Munck A, Iron A, Grasemann H, Schuster A, Cornel MC, ten Kate LP. CFTR mutations in Turkish and North African cystic fibrosis patients in Europe: implications for screening. Genetic Testing 2008;12:25-35.

Lakeman P, Plass AM, Henneman L, Bezemer PD, Cornel MC, ten Kate LP. Three-month follow-up of Western and non-Western participants in a study on preconceptional ancestry-based carrier couple screening for cystic fibrosis and hemoglobinopathies in the Netherlands. Genet Med. 2008;10:820-30.

Soini S, Aymé S, Matthijs G and Public and Professional Policy Committee of European Society of Human Genetics (incl. Cornel MC as collaborator) and Patenting and Licensing Committee. Patenting and licensing in genetic testing: ethical, legal, and social issues. Eur J Hum Genet. 2008;16 Suppl 1:S10-50.

Van Ommen GB, Cornel MC. Recreational genomics? Dreams and fears on genetic susceptibility screening. Eur J Hum Genet 2008; 16:403-4. 

Achterbergh R, Lakeman P, Stemerding D, Moors EHM, Cornel MC. Implementation of preconceptional carrier screening for cystic fibrosis and haemoglobinopathies: A sociotechnical analysis. Health Policy 2007; 83: 277-286. 

Lakeman P, Henneman L, Bezemer PD, Cornel MC, ten Kate LP. Developing and optimizing a decisional instrument using self-reported ancestry for carrier screening in a multi-ethnic society. Genetics in Medicine 2006; 8:502-9.

Meijer WM, Cornel MC, Dolk H, de Walle HEK, Armstrong NC, de Jong-van den Berg LTW, EUROCAT Working Group. The potential of the European network of congenital anomaly registers (EUROCAT) for drug safety surveillance: a descriptive study. Pharmacoepidemiology and Drug Safety 2006;15(9):675-82.

Soini S, Ibarreta D, Anastasiadou V, Aymé S, Braga S, Cornel M, Coviello DA, Evers-Kiebooms G, Geraedts J, Gianaroli L, Harper J, Kosztolanyi G, Lundin K, Rodrigues-Cerezo E, Sermon K, Sequeiros J, Tranebjaerg L, Kaariainen H. The interface between assisted reproductive technologies and genetics: technical, social, ethical and legal issues. Eur J Hum Genet 2006;14(5):588-645.

van Esch SCM, Cornel MC, Snoek FJ. Type 2 diabetes and inheritance: what information do diabetes organizations provide on the Internet? Diabet Med. 2006;23(11):1233-8. 

Baars MJH, Scherpbier AJJA, Schuwirth LW, Henneman L, Beemer FA, Cobben JM, Hennekam RCM, Verweij MMJJ, Cornel MC, ten Kate LP. Deficient knowledge of genetics relevant for daily practice among medical students nearing graduation. Genetics in Medicine 2005;7(5): 295-301.

Cornel MC, De Smit DJ, De Jong-van den Berg LTW. Folic acid – the scientific debate as a base for public health policy. Reproductive Toxicology 2005;20:411-415.

Weijers-Poppelaars FAM, Wildhagen MF, Henneman L, Cornel MC, ten Kate LP. Preconception Cystic Fibrosis Carrier Screening: Costs and Consequences. Genetic Testing 2005;9:158-66.

Heuterman JSJ, de Walle HEK, Poortvliet MC, Bouwman K, Cornel MC. The age at postnatal diagnosis of down syndrome in the northern Netherlands for the period of 1981-2000. Community Genet. 2004;7:55-59.

Kroes HY, Olney RS, Rosano A, Liu Y, Castilla EE, Cocchi G, De Vigan C, Martinez-Frias ML, Mastroiacovo P, Merlob P, Mutchnick O, Ritvanen A, Stoll C, van Essen AJ, Cobben JM, Cornel MC. Renal defects and limb deficiencies in 197 infants: Is it possible to define the “acrorenal syndrome”? Am J Med Genet 2004; 129:149-55.

Poppelaars FAM, Cornel MC, Ten Kate LP. Current practice and future interest of general practitioners and prospective parents in preconception care in the Netherlands. Fam Pract 2004;21:307-309.

Poppelaars FAM, Henneman L, Adèr HJ, Cornel MC, Hermens RPMG, Van der Wal G, Ten Kate LP. Preconceptional cystic fibrosis carrier screening: attitudes and intentions of the target population. Genetic Testing 2004;8: 80-89.

Poppelaars FAM, Adèr HJ, Cornel MC, Henneman L, Hermens RPMG, van der Wal G, Kate LP. Attitudes of potential providers towards preconceptional cystic fibrosis carrier screening. Journal of Genetic Counseling 2004;13:31-44. 

De Walle HEK, Reefhuis J, Cornel MC. Folic acid prevents more than neural tube defects: A registry-based study in the Northern Netherlands. Eur J Epidemiol 2003;18: 279-280.

Poppelaars FAM, Henneman L, Adèr HJ, Cornel MC, Hermens RPMG, van der Wal G, Ten Kate LP. How should preconceptional cystic fibrosis carrier screening be provided? Opinions of potential providers and the target population. Community Genet 2003;6:157-165.

Poppelaars FA, Van der Wal G, Braspenning JC, Cornel MC, Henneman L, Langendam MW, Ten Kate LP. Possibilities and barriers in the implementation of a preconceptional screening programme for cystic fibrosis carriers: a focus group study. Public Health 2003;117:396-403.

Van der Pal-de Bruin KM, de Walle HE, de Rover CM, Jeeninga W, Cornel MC, de Jong-van den Berg LT, Buitendijk SE, Paulussen TG. Influence of educational level on determinants of folic acid use. Paediatr Perinat Epidemiol. 2003;17:256-63. 

Cornel MC. From knowledge to implementation (editorial). Community Genetics 2002;5:5-7.

Kroes HY, Reefhuis J, Cornel MC. Is there an association between maternal carbamazepine use during pregnancy and eye malformations in the child? Epilepsia 2002; 43: 929-31

Marteau TM, Nippert I, Hall S, Limbert C, Reid M, Bobrow M, Cameron A, Cornel MC, Diem M van, Eiben B, Garcia-Minaur S, Goujard J, Kirwan D, McIntosh K, Soothill P, Verschuuren-Bemelmans C, Vigan C de, Walkinshaw S, Abramsky L, Louwen F, Miny P, Horst J. Outcomes of pregnancies diagnosed with Klinefelter syndrome: the possible influence of health professionals. Prenatal Diagnosis 2002; 22: 562-6.

Reefhuis J, de Jong-van den Berg LTW de, Cornel MC. The use of birth defect registries for etiological research: A review. Community Genetics 2002; 5: 13-32.

Walle HEK de, Cornel MC, Jong-van den Berg LTW de. Three years after the Dutch folic acid campaign: growing socio-economic differences. Preventive Medicine 2002; 35: 65-9. 

Stoll C, Rosano A, Botto LD, Erickson D, Khoury MJ, Olney RS, Castilla EE, Cocchi G, Cornel MC, Goujard J, Bermejo E, Merlob P, Mutchinick O, Ritvanen A, Zampino G, Mastroiacovo P. On the symmetry of limb deficiencies among children with multiple congenital anomalies. Ann Genet. 2001;44(1):19-24. 

Arpino C, Brescianini S, Robert E, Castilla EE, Cocchi G, Cornel MC, de Vigan C, Lancaster PAL, Merlob P, Sumiyoshi Y, Zampino G, Renzi C, Rosano A, Mastroiacovo P. Teratogenic effects of antiepileptic drugs: Use of an international database on malformations and drug exposure (MADRE). Epilepsia 2000; 41(11): 1436-1443.

Cornel MC. Wealth and health in relation to birth defects mortality. (Editorial). J Epid Comm Health 2000; 54: 644.

Cornel MC. Reply. Community Genet 2000; 3: 43.

Lorente C, Cordier S, Goujard J et al and the Occupational Exposure and Congenital Malformation Working Group (incl. Cornel MC). Tobacco and alcohol use during pregnancy and risk of oral clefts. Am J Public Health 2000; 90: 415-419.

Lorente C, Cordier S, Bergeret A et al and the Occupational Exposure and Congenital Malformation Working Group (incl. Cornel MC). Maternal occupational risk factors for oral clefts. Scand J Work Environ Health 2000; 26: 137-145.

Reefhuis J, De Walle HEK, De Jong-Van den Berg LTW, Cornel MC and EuroMAP-group. Additional information from parental questionnaires and pharmacy records for registration of birth defects. Eur J Epidemiology 2000; 16: 329-336.

Rosano A, Botto LD, Olney RS, Khoury MJ, Ritvanen A, Goujard J, Stoll C, Cocchi G, Merlob P, Mutchinick O, Cornel MC, Castilla EE, Martinez-Frias ML, Zampino G, Erickson JD, Mastroiacovo P. Limb defects associated with major congenital anomalies : Clinical and epidemiological study from the International Clearinghouse for Birth Defects Monitoring Systems. Am J Med Genet 2000; 93: 110-116.

Rijnders LJM, Boonstra AM, Groothoff JW, Cornel MC, Eisma WH. Lower limb deficient children in the Netherlands: epidemiological aspects. Prosthetics and Orthotics International 2000; 24: 13-18.

Sijmons RH, Boonstra AE, Reefhuis J, Hordijk-Hos JM, De Walle HEK, Oosterwijk JC, Cornel MC. Accuracy of family history of cancer: clinical genetic implications. Eur J Hum Genet 2000; 8: 181-186.

Van der Pal-de Bruin KM, De Walle HEK, Jeeninga W, De Rover C, Cornel MC, De Jong-van den Berg LTW, Schouten J, Brand R, Buitendijk SE. The Dutch ‘Folic Acid Campaign’-have goals been achieved? Paediatric and Perinatal Epidemiology 2000;14:111-117.

Wortelboer MJM, De Wolf BTHM, Verschuuren-Bemelmans CC, Reefhuis J, Mantingh A, Beekhuis JR, Cornel MC. Trends in live birth prevalence of Down syndrome in the Northern Netherlands 1987-96: the impact of screening and prenatal diagnosis. Prenat Diagn 2000; 20: 709-713.

Cornel MC. Common language for measures of occurrence of congenital anomalies and genetic diseases: Incidence or birth prevalence. Community Genet 1999; 2:162-164.

De Jong-van den Berg LTW, Feenstra N, Toft Sorensen H, Cornel MC, and the EuroMAP Group. Improvement of drug exposure data in a registration of congenital anomalies. Pilot-study: Pharmacist and mother as sources for drug exposure data during pregnancy. Teratol 1999;60:33-6.

De Jong-van den Berg LTW, Van der Zee AH, Schaafsma E, De Smit D, Anderson C, Cornel MC. Counselling women about periconceptional use of folic acid: the role of the community pharmacist can be improved. Int J Pharm Pract 1999; 7: 138-42.

De Walle HEK, Cornel MC, de Smit DJ, de Jong-Van den Berg, LTW. Preconceptional use of folic acid amongst women of advanced maternal age (Correspondence). Prenat Diagn 1999;19:996-7.

De Walle HEK, De Jong-van den Berg LTW, Cornel MC. Periconceptional folic acid intake in the northern Netherlands. The Lancet 1999;353:1187.

De Walle HEK, Van der Pal KM, De Jong-Van den Berg LTW, Jeeninga W, Schouten JSAG, De Rover CM, Buitendijk SE, Cornel MC. Effect of mass media campaign to reduce socioeconomic differences in women’s awareness and behaviour concerning use of folic acid: cross sectional study. BMJ 1999;319:291-2.

Dolk H, Nichols R and a EUROCAT Working Group (including Cornel MC). Evaluation of the impact of Chernobyl on the prevalence of congenital anomalies in 16 regions of Europe. Int J Epidemiol 1999; 28: 941-948.

Reefhuis J, De Walle HEK, Cornel MC. Artefactual increasing frequency of omphaloceles in the Northern Netherlands: lessons for systematic analysis of apparent epidemics. Int J Epidemiology 1999;28:258-62.

Reefhuis J, Zandwijken GRJ, De Walle HEK, Cornel MC. Birth defect and risk factor surveillance in the Northern and Southwestern Netherlands. Community Genet 1999; 2: 97-108.

Rosano A, Smithells D, Cacciani L, Botting B, Castilla E, Cornel MC, Erickson D, Goujard J, Irgens L, Merlob P, Robert E, Siffel C, Stoll C, Sumiyoshi Y. Time trends in neural tube defects prevalence in relation to preventive strategies: in international study. J Epid Comm Health 1999; 53(10): 630-5. 

De Jong-van den Berg LTW, De Walle HEK, Van der Pal-de Bruin KM, Buitendijk SE, Cornel MC. Increasing awareness and behaviour towards periconceptional folic acid consumption in The Netherlands from 1994 to 1995. Eur J Clin Pharmacol 1998;54:329-331.

De Walle HEK, Van der Pal KM, De Jong-van den Berg LTW, Schouten J, De Rover CM, Buitendijk SE, Cornel MC. Periconceptional folic acid in the Netherlands in 1995. Socio-economic differences. J Epid Comm Health 1998; 52: 826-827.

Reefhuis J, De Walle HEK, Cornel MC and EUROCAT Working Group. Maternal smoking and deformities of foot: results of the EUROCAT study. Am J Public Health 1998; 88:1554-5.

Cornel MC, Erickson JD. Comparison of national policies on periconceptional use of folic acid to prevent spina bifida and anencephaly (SBA). Teratol 1997;55(2):134-7.

Van der Veen WJ, Beekhuis JR, Cornel MC, Mantingh A, De Walle HEK, De Wolf BTHM. A demographic approach to the assessment of Down syndrome screening performance. Prenatal Diagnosis 1997;17(8):717-24.

Cornel MC, Erickson JD, Khoury MJ, James LM, Liu Y. Population-based birth-defect and risk-factor surveillance: data from the Northern Netherlands. International Journal of Risk & Safety in Medicine 1996;8(3):197-209.

Stoll C, Calzolari E, Cornel MC, Garcia-Minaur S, Garne E, Nevin N. A study on limb reduction defects in six european regions. Ann Genet 1996;39(2):99-104.

Calzolari E, Bianchi F, Dolk H, Milan M, Lechat MF, Leurquin P, Goyens S, Astolfi G, Volpato S, Ayme S, et al. Omphalocele and gastroschisis in Europe: A survey of 3 million births 1980-1990. American Journal Medical Genetics 1995;58(2):187-94.

De Jong-van den Berg LTW, Cornel MC, Tymstra T, Buitendijk SE. Folate prophylaxis in pregnancy. Lancet 1995;346(November 4):1227-8.

Klok ER, Tymstra T, Cornel MC, De Walle HEK, De Jong-van den Berg LTW. Women's opinions on the use of folic acid. International Journal of Risk & Safety in Medicine 1995;7(3):211-8.

Stoll C, Aymé S, Beckers R, Calzolari E, Cornel M, Cushieri A, De Wals P, Dolk H, Dott B, Galanti C, et al. Distribution of single organ malformations in European populations. EUROCAT Working Group. Ann Genet. 1995;38(1):32-43.

Sturkenboom MCJM, Stricker BHC, De Jong-van den Berg LTW, Cornel MC, Wesseling H. The role of pharmacists in the recruitment of a cohort for postmarketing surveillance. Pharmacy World & Science 1995;17(4):126-32.

Cornel MC, for the EUROCAT Working group. Variation in prenatal cytogenetic diagnosis: policies in 13 european countries, 1989-1991. Prenatal Diagnosis 1994;14(5):337-44.

Sturkenboom MCJM, De Jong-van den Berg LTW, Van Voorst-Vader PC, Cornel MC, Stricker BHCH, Wesseling H. Inability to detect plasma etretinate and acitretin is a poor predictor of the absence of these teratogens in tissue after stopping acitretin treatment. Brit J Clin Pharmaco 1994;38:229-35.

Sturkenboom MCJM, De Jong-van den Berg LTW, Cornel MC, Stricker BHC, Wesseling H. Communicating a drug alert. A case study on acitretin in The Netherlands. Eur J Clin Pharmacol 1994;47:125-32.

Cornel MC, Breed ASPM, Beekhuis JR, Te Meerman GJ, Ten Kate LP. Down syndrome: effects of demographic factors and prenatal diagnosis on the future livebirth prevalence. Human Genetics 1993;92:163-8. 

Cornel MC, De Walle HEK, Ten Kate LP. Ten years of experience with registration of congenital anomalies in the northern Netherlands by EUROCAT. Methodology. T voor Sociale Gezondheidszorg 1992;70:637-44.

De Vries CS, De Walle HEK, Cornel MC, De Jong-van den Berg LTW. Registration of drug use in a birth defect monitoring system: a priority worthy of emphasis! International Journal of Risk & Safety in Medicine 1993;4:27-34.

Haring DAJP, Cornel MC, Van der Linden JC, Van Vugt JMG, Kwee ML. Acardius acephalus after induced ovulation: a case report. Teratol 1993;47:257-62.

Bouvy ML, Sturkenboom MCJM, Cornel MC, De Jong-van den Berg LTW, Stricker BHC, Wesseling H. Acitretin (Neotigason). A review of pharmacokinetics and teratogenicity and hypothesis on metabolic pathways. Pharm Weekbl [Sci] 1992;14:33-7.

Cornel MC, Spreen JA, Meijer I, Spauwen PHM, Dhar BK, T