A-CaRe Study 2. Physical exercise during Adjuvant Chemotherapy Effectiveness Study (PACES) (WC2008-031)

A-CaRe Study 2. Physical exercise during Adjuvant Chemotherapy Effectiveness Study (PACES)

Background

Starting date: 01/04/2010

Cancer chemotherapy is frequently associated with a decline in general physical condition, exercise tolerance, and muscle strength, and with an increase in fatigue. While accumulating evidence suggests that physical activity and exercise interventions during chemotherapy treatment may contribute to preservation of physical fitness and strength, the result of studies conducted to date have not been entirely consistent. Additional research is needed to determine the optimal intensity of exercise training programs, in general, and in particular the relative effectiveness of supervised, outpatient clinic or physical therapy practice/based’ versus home-based programs. Also, the large majority of studies carried out thus far have focused on women undergoing treatment for beast cancer only. Little is known about the possible beneficial effects of exercise interventions among other patient populations undergoing chemotherapy (e.g. colon cancer). 

This study is part of the Alp D’Huzes Cancer Rehabilitation Research program (A-CaRe) coordinated by the EMGO Institute for Health and Care Research.