A-CaRe Study 4. Quality of Life in Motion (QLIM): A combined physical exercise and psychosocial training program to improve physical fitness in children with cancer (WC2008-042)

Background

Starting date: 01/05/2009 Advances in treatment of childhood cancer have dramatically increased long-term survival. As a result, the numbers of childhood cancer survivors (CCS) are growing. Unfortunately, as a consequence approximately 75% of long-term CCS have at least one adverse health effect. Prevention or reduction of acute and long-term adverse health effects should be pursued in order to maintain or improve health-related quality of life (HrQOL). Physical fitness has been shown to be reduced both during and after childhood cancer with physical inactivity being one of the most prominent causes. Physical inactivity may lead to obesity, fatigue, a poor skeletal and/or mental health, and ultimately a compromised HrQOL. Therefore, prevention of inactivity by increasing physical fitness, both during and following treatment, is essential. Rehabilitation programs in adult cancer patients report positive effects on physical fitness and HrQOL. However, such a program does not exist for childhood cancer patients.