The new Hoorn Study: prevalence and determinants of impaired glucose regulation

Objectives

Main aim
The main aim of the New Hoorn Study is to create a new cohort study on diabetes in the Netherlands. This cohort will be followed for several years to study the longitudunal relations between several risk factors and diabetes. 

Specific research questions
1. To study the prevalence of impaired glucose regulation and type 2 diabetes in the general population aged 40 to 65 years, and to compare these prevalence rates with those in the first Hoorn Study.
2. To study differences in various anthropometric and metabolic population characteristics (with special attention to lifestyle factors and body composition) between subgroups with a different glucose status and between the first and new Hoorn Study
3. To study differences in cardiovascular risk profile in participants of the Hoorn Study and New Hoorn Study.
3. To study the correlations between HbA1c, fasting glucose and 2-hour postload glucose in the general population and to determine wether HbA1c can be used to diagnose diabetes.